| Cat. No. |
Product Name |
Information |
| PC-35403 |
Omidenepag Isopropyl
EP2 agonist
|
Omidenepag Isopropyl (DE-117, OMDI) is the prodrug of Omidenepag, which is a potent, selective agonist human EP2 receptor. |
| PC-35402 |
Omidenepag
EP2 agonist
|
Omidenepag (UR-7276) is a potent, selective agonist human EP2 receptor with binding IC50/EC50 of 10/1.7 nM, >500-fold selectivity over EP1, EP3 and EP4 receptors. |
| PC-35353 |
RO1138452
IP receptor inhibitor
|
RO1138452 is a potent, selective antagonist of prostacyclin receptor (IP receptor), inhibits carbaprostacylin-stimulated c-AMP accumulation in human SH-SY5Y neuroblastoma cells with pKb of 8.8. |
| PC-35221 |
CR6086 sodium
EP4 antagonist
|
CR6086 sodium (CR-6086) is a potent, selective prostaglandin E2 receptor 4 (EP4) antagonist with Ki of 16.6 nM (hEP4 receptor), inhibits PGE2-stimulated cAMP production with IC50 of 22 nM. |
| PC-35079 |
OBE022
PGF2α receptor antagonist
|
OBE022 (Ebopiprant, OBE-022) is a potent, highly selective, orally active antagonist of the contractile PGF2α prostaglandin receptor with Kb of 5.9 nM, shows no activity for other human PG receptors subtypes. |
| PC-63545 |
E7046
EP4 antagonist
|
E7046 (Palupiprant, ER-886046) is a potent, selective, orally bioavailable EP4 receptor antagonist with IC50 of 13.5 nM, Ki of 23.14 nM. |
| PC-63431 |
ADC-3680
CRTH2 inhibitor
|
ADC-3680 (PTR-36, ADC-3680B) is a potent, selective prostaglandin D2 receptor (DP2, CRTH2) antagonist for the treatment of asthma.. |
| PC-63430 |
MK-1029
CRTH2 inhibitor
|
MK-1029 is a potent, selective prostaglandin D2 receptor (DP2, CRTH2) antagonist for the treatment of asthma. |
| PC-63365 |
ONO-DI 004
EP1 agonist
|
ONO-DI 004 is a potent, selective EP1 agonist.. |
| PC-63350 |
GSK726701A
EP4 agonist
|
GSK726701A is a novel potent, selective EP4 receptor partial agonist with pEC50 of 7.4 in cAMP accumulation assay, >100-fold against a set of other prostaglandin receptors (EP1-3, DP1, FP, IP and TP). |
| PC-43293 |
Dinoprost tromethamine salt
|
Dinoprost (Prostaglandin F2α, PGF2α) is a naturally occurring prostaglandin used to induce labor and as an abortifacient, causes contraction of vascular, bronchial, intestinal, and myometrial smooth muscle, and also exhibits potent luteolytic activity.. |
| PC-43292 |
Dinoprost
|
Dinoprost (Prostaglandin F2α, PGF2α) is a naturally occurring prostaglandin used to induce labor and as an abortifacient, causes contraction of vascular, bronchial, intestinal, and myometrial smooth muscle, and also exhibits potent luteolytic activity. |
