| Cat. No. |
Product Name |
Information |
| PC-28337 |
SQ-030
cPGES inhibitor
|
SQ-030 is a potent, hepatocyte-specific cytosolic prostaglandin E synthase (cPGES) inhibitor with SPR KD of 0.315 uM. |
| PC-25867 |
AGU661
mPGES-1 inhibitor
|
AGU661 (AGU-661) is a potent microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitor, inhibits the enzyme activity of mPGES-1 in microsomes with IC50 of 0.22 nM in cell-free assays. |
| PC-23561 |
AGU654
mPGES-1 inhibitor
|
AGU654 (AGU-654) is a potent, selective microsomal prostaglandin E2 synthase 1 (mPGES-1) inhibitor with IC50 of 2.9 nM in cell-free assays. |
| PC-23101 |
Friluglanstat
mPGES-1 inhibitor
|
Friluglanstat (NS-580) is a selective, orally available membrane-associated prostaglandin E synthase-1 (mPGES-1) inhibitor. |
| PC-22479 |
mPGES1-IN-7
mPGES-1 inhibitor
|
mPGES1-IN-7 (Compound III) is a selective murine/human microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor with IC50 of 0.9/0.09 uM respectively. |
| PC-22237 |
TG554
mPGES-1 inhibitor
|
TG554 is a potent, selective microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitor with IC50 of 5.6 nM, suppresses leukotriene (LT) biosynthesis at low µM concentrations. |
| PC-20721 |
PF-4693627
mPGES-1 inhibitor
|
PF-4693627 is a potent, selective and orally bioavailable mPGES-1 inhibitor with IC50 of 3 nM. |
| PC-20720 |
UT-11
mPGES-1 inhibitor
|
UT-11 is a potent microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor, inhibits PGE2 production from human SK-N-AS and murine BV2 cells induced by LPS with IC50 of 0.1 and 2.0 uM, respectively. |
| PC-20005 |
mPGES-1 inhibitor UK-4b
mPGES-1 inhibitor
|
mPGES-1 inhibitor UK-4b is a potent, hgihly selective and orally bioavailable inhibitor of human and mouse mPGES-1 enzymes with IC50 of 33 and 157 nM, respectively, effectively decreases carrageenan-stimulated PGE2 over-production. |
| PC-49705 |
mPGES-1 inhibitor PBCH
mPGES-1 inhibitor
|
PBCH is a selective small-molecule inhibitor of mPGES-1, which is potent and can effectively inhibit both human and rodent orthologs. |
| PC-49642 |
TAS-204
H-PGDS inhibitor
|
TAS-204 (TAS204) is a potent, specific hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, inhibits recombinant human H-PGDS with IC50 of 24.0 nM. |
| PC-49641 |
TAS-205 monohydrate
H-PGDS inhibitor
|
TAS-205 (Pizuglanstat, TAS205) is a potent, specific hematopoietic prostaglandin D synthase (H-PGDS) inhibitor with IC50 of 55.8 nM, does not inhibit LPGDS at 100 uM. |
