| Cat. No. |
Product Name |
Information |
| PC-70048 |
CK-0106023
KSP inhibitor
|
CK-0106023 (CK0106023) is a potent, specific, allosteric inhibitor of KSP motor domain ATPase with Ki of 12 nM. |
| PC-70047 |
HR22C16
Eg5 inhibitor
|
HR22C16 (Monastroline) is a potent, selective and cell permeable inhibitor of mitotic kinesin Eg5 with IC50 of 0.8 uM, does not interact with other microtubule motor proteins. |
| PC-42514 |
GSK923295
CENP-E inhibitor
|
GSK-923295 (GSK923295) is the first potent, allosteric inhibitor of CENP-E kinesin motor ATPase activity with Ki of 3.2 nM. |
| PC-45640 |
PF-2771
CENP-E inhibitor
|
PF-2771 is a potent, selective centromere protein E (CENP-E) inhibitor with IC50 of 16.1 nM. |
| PC-45755 |
Dimethylenastron
Eg5 inhibitor
|
Dimethylenastron is a small molecule inhibitor of the mitotic kinesin Eg5. |
| PC-42308 |
Monastrol
Eg5 inhibitor
|
Monastrol is a potent, specific, allosteric and reversible mitotic kinesin Eg5 inhibitor with IC50 of 14 uM (microtubule motility inhibition). |
| PC-45861 |
Ispinesib
Eg5 inhibitor
|
Ispinesib (SB-715992) is a potent, selective, cell-permeable, allosteric inhibitor of Eg5 (mitotic kinesin KSP) with Ki of 2.3 nM. |
| PC-45767 |
K858
Kinesin Eg5 inhibitor
|
K858 is a potent, selective inhibitor of mitotic kinesin Eg5 ATPase activity with IC50 of 1.3 uM. |
| PC-25961 |
VLS-1488
KIF18A inhibitor
|
VLS-1488 (KIF18A-IN-6) is a potent, selective and orally active KIF18A inhibitor, inhibits KIF18A microtubule-dependent ATPase activity with IC50 of 16 nM. |
| PC-25729 |
ATX020
KIF18A inhibitor
|
ATX020 (ATX-020) is a potent, selective and orally efficacious KIF18A (kinesin-like protein 18A) inhibitor with IC50 of 0.11 uM and 0.16 uM for human and rat KIF18A respectively. |
| PC-24692 |
CW069
KIFC1 inhibitor
|
CW069 (CW-069) is a specifc, allosteric small moelule inhibitor of microtubule motor protein HSET (encoded by KIFC1 in humans and Kifc5a in mice) with IC50 of 75 uM. |
| PC-23792 |
VLS-1272
KIF18A inhibitor
|
VLS-1272 is a potent, ATP non-competitive, orally bioavailable, and highly selective inhibitor of KIF18A ATPase activity with IC50 of 41 nM and 8.8 nM for human and murine KIF18A (0.1 mM ATP), respectively. |
