Hippo (inhibitors, antagonists, agonists)-ProbeChem.com

Request The Product List ofHippo Hippo

Cat. No.	Product Name	Information
PC-38111	VT02484 LATS inhibitor	VT02484 is the negative control compound of VT02956, which is a highly potent Hippo pathway kinase LATS inhibitor..
PC-38110	VT02956 LATS inhibitor	VT02956 is a potent, specific inhibitor of Hippo pathway kinase LATS with IC50 of 0.76 nM (LATS1) and 0.52 nM (LATS2), respectively.
PC-42188	XMU-MP-1 MST1/2 inhibitor	XMU-MP-1 is a potent, selective, and ATP-competitive inhibitor of the mammalian Hippo orthologs, Sterile 20-like kinases MST1 and MST2 with IC50 of 71.1 nM and 38.1 nM, respectively.
PC-25218	LPi-1 LATS1/2 inhibitor	LPi-1 is a highly potent, selective and ATP-competitive inhibitor of large tumor suppressor kinases (LATS1 and LATS2) with IC50 of 4.4 nM and 1.3 nM respectively, abrogates the LATS1/2-mediated YAP1 inhibition in cells, activates YAP1 and its paralogue TAZ in vitro and in vivo.
PC-24897	MST3 inhibitor LD-1 MST3 inhibitor	MST3 inhibitor LD-1 is a potent, selective inhibitor of MST3 protein kinase (mammalian Ste20-like protein kinase 3, STK24) with IC50 of 122.4 nM.
PC-21869	UNC-BE4-017 STK3 inhibitor	UNC-BE4-017 is a selective STK3 small-molecule inhibitor, also potently inhibits JAK1, JAK2, and JAK3, but not other kinases in a panel of 48 kinases.

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