Hec1/Nek2 (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-61480	INH154 Hec1/Nek2 inhibitor	INH154 is a novel small molecules disrupting Hec1/Nek2 interaction, inhibits HeLa and MDA-MB-468 cancer cells growth with IC50 of 0.20 and 0.12 uM, respectively.
PC-61479	Nek2 inhibitor 72 Nek2 inhibitor	Nek2 inhibitor 72 is a potent, ATP-competitive and relative selective Nek2 inhibitor with IC50 of 0.27 uM.
PC-61478	Nek2 inhibitor 3a Nek2 inhibitor	Nek2 inhibitor 3a is a potent, relatively selective Nek2 inhibitor with IC50 of 82.74 nM in cell-free assays.
PC-61477	Nek2 inhibitor 11 Nek2 inhibitor	Nek2 inhibitor 11 is a potent, ATP-competitive and relative selective Nek2 inhibitor with IC50 of 0.67 uM.
PC-42194	NEK2 inhibitor INH6 Hec1-Nek2 inhibitor	NEK2 inhibitor INH6 is a small molecule inhibitor of Nek2/Hec1 that inhibits cell growth of MB231, MB468, HeLa and K562 cells with IC50 of 1.7, 2.1, 2.4 and 2.5 uM, respectively.
PC-27623	Nek2 inhibitor Compound 53 NEK2 inhibitor	Nek2 inhibitor Compound 53 is a potent small molecule inhibitor of Nek2 with IC50 of 1.42 uM, >50-fold more potently than strong R-spine mutant Nek7SRS and Nek7WT.
PC-27600	MBM-55S NEK2 inhibitor	MBM-55S (MBM-55 succinic acid salt) is a potent, selective NIMA-related kinase 2 (NEK2) inhibitor with IC50 of 1.0 nM.

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