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NEK2 inhibitor INH6

Chemical Structure : NEK2 inhibitor INH6

CAS No.: 1001753-24-7

NEK2 inhibitor INH6 (INH6)

货号: PC-42194Not For Human Use, Lab Use Only.

NEK2 inhibitor INH6 is a small molecule inhibitor of Nek2/Hec1 that inhibits cell growth of MB231, MB468, HeLa and K562 cells with IC50 of 1.7, 2.1, 2.4 and 2.5 uM, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

INH6 is a small molecule inhibitor of Nek2/Hec1 that inhibits cell growth of MB231, MB468, HeLa and K562 cells with IC50 of 1.7, 2.1, 2.4 and 2.5 uM, respectively.
INH6 triggers mitotic abnormalities and induces apoptosis.

物理化学性质&存储条件

分子量 322.424
分子式 C19H18N2OS
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzamide, N-[4-(2,4,6-trimethylphenyl)-2-thiazolyl]-

参考文献

1. Qiu XL, et al. J Med Chem. 2009 Mar 26;52(6):1757-67.

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