| Cat. No. |
Product Name |
Information |
| PC-45745 |
Adomeglivant
GCGR antagonist
|
Adomeglivant (LY-2409021) is a potent, selective, orally active, small-molecule antagonist of human glucagon receptor with Ki of 6.66 nM. |
| PC-45839 |
GRA Ex-25
Glucagon receptor inhibitor
|
GRA Ex-25 is a potent glucagon receptor inhibitor with IC50 of 56 and 55 nM for rat and human glucagon receptors. |
| PC-42112 |
Glucagon receptor antagonist 1
|
Glucagon receptor antagonist 1 is a highly potent glucagon receptor antagonist. |
| PC-45758 |
PF-06291874
Glucagon receptor antagonist
|
PF-06291874 (PF-6291874) is a highly potent glucagon receptor antagonist with Ki of 14 nM for hGCGR. |
| PC-24419 |
DA-302168S
GLP-1R agonist
|
DA-302168S is a potent, selective and orally bioavailable agonist of GLP-1R with EC50 of 1.32 nM in luciferase assay in HEK293 cells expressing hGLP-1R. |
| PC-24418 |
DD202-114
GLP-1R agonist
|
DD202-114 (HDM1002) is a potent and selective glucagon-like peptide-1 receptor (GLP-1R) agonist with EC50 of 0.03 nM in cAMP assay in HEK293 cells expressing hGLP-1R. |
| PC-24125 |
ECC5004
GLP-1 agonist
|
Elecoglipron (ECC5004/AZD5004) is a novel small‐molecule GLP‐1 receptor agonist, binds to the human GLP‐1R with IC50 of 2.4 nM, displays a full agonist profile with a potency of 2.1 nM. |
| PC-23689 |
Survodutide
GCGR/GLP-1R agonist
|
Survodutide (BI 456906) is a highly potent GCGR/GLP-1R dual agonist with EC50 of 0.52/0.60 nM respectively (human GCGR/GLP-1R), exhibits robust weight loss and glycaemic control activity. |
| PC-23685 |
GLP-1 receptor agonist 2
GLP-1 agonist
|
GLP-1 receptor agonist 2 is a potent, selective GLP-1 receptor agonist, shows potential for GLP-1 receptor - mediated diseases, such as pre-diabetes, type II diabetes, non-alc. steatohepatitis, non-alc. fatty liver disease, obesity, cardiovascular and other diseases. |
| PC-23667 |
Aleniglipron
GLP-1R agonist
|
Aleniglipron (GSBR-1290) is a fully biased, orally available, potent GLP-1R agonist with binding Ki of <10 nM and cAMP EC50 of <0.1 nM. |
| PC-23574 |
Avexitide
GLP-1R antagonist
|
Avexitide (Exendin-(9-39)) is a selective glucagon-like peptide 1 receptor (GLP-1R) antagonist, competes with endogenous GLP-1 for binding to GLP-1 receptors with Ki of 4.0 nM. |
| PC-23495 |
BETP
GLP-1 agonist
|
BETP is a potent, allosteric activator/agonist of glucagon-like peptide-1 (GLP-1) receptor with EC50 of 0.66 and 0.755 μM for human and rat GLP-1 receptor, respectively, also inhibits importin α1 import and importin β1 dependent cargo import with EC50 of μM uM in phenotypic importin α1 translocation assays. |
