| Cat. No. |
Product Name |
Information |
| PC-26354 |
Risimtinib
FGFR inhibitor
|
Risimtinib (Compound 19a) is a highly potent FGFR inhibitor with IC50 of 2.1 nM against FGFR1, and 14.9 nM against the FGFR1-positive KG-1cancer cell. |
| PC-26084 |
FGFR3 covalent inhibitor 10s
FGFR3 inhibitor
|
FGFR3 covalent inhibitor 10s is a selective, covalent FGFR3 inhibitor with IC50 of 6.8 nM, has 5-60-fold selectivity over FGFR1/2/4. |
| PC-25243 |
TCB-32
bFGF mimic, FGFR1 activator
|
TCB-32 is an agonistic small molecules that mimic binding of basic fibroblast growth factor (bFGF), shows a strong proliferative effect in NIH 3T3 cells, activates the same FGFR1-signaling pathway as bFGF. |
| PC-22625 |
FGF trap compound 57
FGF trap inhibitor
|
FGF trap compound 57 is a non-steroidal NSC12 derivative as FGF trap small molecule, shows anti-myeloma activity. |