| Cat. No. |
Product Name |
Information |
| PC-28454 |
Vibliome Therapeutics HIPK4 inhibitor
HIPK4 inhibitor
|
Vibliome Therapeutics HIPK4 inhibitor is a potent, selective small molecule Homeodomain-interacting protein kinase 4 (HIPK4) inhibitor (>95% inhibiton at 5 uM). |
| PC-27003 |
DYRK inhibitor FC-3
DYRK1A inhibitor
|
DYRK inhibitor FC-3 is a potent, selective, reversible, ATP-competitive inhibitor of Dual-specificity tyrosine-regulated kinases (DYRKs) with IC50 of 53 nM (DYRK1A). |
| PC-27002 |
DYRK inhibitor FC-2
DYRK1A inhibitor
|
DYRK inhibitor FC-2 is a potent, selective, reversible, ATP-competitive inhibitor of Dual-specificity tyrosine-regulated kinases (DYRKs) with IC50 of 19 nM (DYRK1A). |
| PC-26800 |
ZJCK-6-72
DYRK1A inhibitor
|
ZJCK-6-72 is a highly potent, orally bioavailable, blood-brain barrier (BBB) permeable DYRK1A inhibitor with IC50 of 8.64 nM. |
| PC-26298 |
ZRMQ-22
DYRK1A inhibitor
|
ZRMQ-22 is a highly potent DYRK1A inhibitor with IC50 of 0.35 nM, concentration-dependently inhibits nitric oxide (NO) production in LPS-stimulated BV2 cells with IC50 of 1 uM. |
| PC-25697 |
MU135
HIPK inhibitor
|
MU135 is a potent, highly selective Homeodomain-interacting protein kinases (HIPKs) inhibitor with IC50 of 248/119/476 nM for HIPK1/HIPK12/HIPK13, repectively. |
| PC-25696 |
XRF-1021
HIPK2 inhibitor
|
XRF-1021 is a potent inhibitor of homeodomain-interacting protein kinase 2 (HIPK2) with IC50 of 0.18 uM, suppresses HIPK2 and blocks TGF-β/Smad3, NF-κB, Wnt/β-catenin, and Notch signaling. |
| PC-25353 |
DYRK1A/1B inhibitor 8h
DYRK1A/DYRK1B inhibitor
|
DYRK1A/1B inhibitor 8h is a potent, selective DYRK1A/DYRK1B inhibitor with IC50 of 5 nM and 3 nM respectively. |
| PC-23759 |
SM15685
DYRK1A/B inhibitor
|
SM15685 is a highly selective and potent, oral, brain-penetrant DYRK1A/B inhibitor with IC50 of 1 nM (DYRK1A). |
| PC-23353 |
NSC361563
DYRK1A inhibitor
|
NSC361563 is a potent and selective DYRK1A inhibitor with IC50 of 1.38 uM. |
| PC-23236 |
DYR530
DYRK1 inhibitor
|
DYR530 is a potent, selective inhibitor of DYRK1 with Kd of 0.91 nM (DYRK1A). |
| PC-23235 |
DYR533
DYRK1 inhibitor
|
DYR533 is a potent, selective inhibitor of DYRK1 with Kd of 1.4 nM (DYRK1A), blocks mnb phosphorylation of human Tau expressed in Drosophila neurons. |
