| Cat. No. |
Product Name |
Information |
| PC-24136 |
Fosrugocrixan
CX3CR1 antagonist
|
Fosrugocrixan is a potent, selective antagonist of CX3C chemokine receptor 1 (CX3CR1) with antiinflammatory activity. |
| PC-24077 |
IDOR-1136-517
CCR8 antagonist
|
IDOR-1136-5177 is a highly potent, selective CCR8 antagonist with IC50 of 2 nM (hCCR8). |
| PC-23972 |
Reparixin L-lysine salt
CXCR1/2 inhibitor
|
Reparixin L-lysine salt (Repertaxin) is a potent, selective, non-competitive allosteric inhibitor of CXCL8 receptor CXCR1 and CXCR2 activation with IC50 of 1 nM and 100 nM, respectively. |
| PC-23971 |
Reparixin
CXCR1/2 inhibitor
|
Reparixin (Repertaxin) is a potent, selective, non-competitive allosteric inhibitor of CXCL8 receptor CXCR1 and CXCR2 activation with IC50 of 1 nM and 100 nM, respectively. |
| PC-23688 |
RS504393
CCR2 antagonist
|
RS504393 is a potent, selective CCR2 antagonist with IC50 of 89 nM, shows no activity against CCR1. |
| PC-23312 |
DZH2
CCR5/CXCR4 inhibitor
|
DZH2 is a dual inhibitor of the chemokine receptors CCR5 and CXCR4 with IC50 of 8.7/13.7 uM in Ca2+-mobilization assays. |
| PC-23198 |
ZK756326 dihydrochloride
CCR8 agonist
|
ZK756326 dihydrochloride is a potent, selective nonpeptide agonist of the CC chemokine receptor CCR8, inhibits the binding of the CCR8 ligand I-309 (CCL1) with IC50 of 1.8 uM. |
| PC-23013 |
OXM2
CCR6 inhibitor
|
OXM2 is a highly selective, allosteric antagonist of CCR6, inhibits CCL20-mediated CCR6+ human T-cell chemotaxis with pIC50 of 6.78. |
| PC-23011 |
SQA1
CCR6 inhibitor
|
SQA1 is a small molecule allosteric antagonist of CCR6, inhibits CCL20-mediated CCR6+ human T-cell chemotaxis with pIC50 of 6.7, also inhibits CXCR2. |
| PC-22933 |
LIH383
ACKR3 agonist
|
LIH383 is a potent, selective atypical chemokine receptor ACKR3 (CXCR7) agonist with EC50 of 0.61 nM in inducing β-arrestin recruitment to ACKR3. |
| PC-22932 |
TC14012
ACKR3 agonist
|
TC14012 is a selective and peptidomimetic CXCR4 antagonist with IC50 of 19.3 nM, also is a specific CXCR7 (ACKR3) agonist with EC50 of 350 nM for recruiting β-arrestin 2 to CXCR7. |
| PC-22931 |
LN5972
ACKR3 agonist
|
LN5972 (LN-5972) is a potent, selective and first-in-class agonist of the atypical chemokine receptor 3 (ACKR3, CXCR7) with β-arrestin EC50 of 3.4 uM. |
