Bcl-2 compound (inhibitors, antagonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-43513	Gossypol BCL-2 inhibitor	Gossypol (BL-193) is a natural phenol that permeates cells and acts as an inhibitor for several dehydrogenase enzymes such as lactate dehydrogenase, NAD-linked enzymes.
PC-42244	S63845 Mcl-1 inhibitor	S63845 is a highly potent, selective Mcl-1 inhibitor with Kd of 0.19 nM, with no appreciable binding affinity to BCL-2 or BCL-XL (Ki>10 uM).
PC-47486	Bax inhibitor peptide V5 Bax inhibitor	Bax inhibitor peptide V5 (Val-Pro-Met-Leu-Lys, BIP-V5) is cell-permeable synthetic peptide inhibitor of Bax conformational change and mitochondrial translocation.
PC-45901	ABT-737 BCL-2 inhibitor	ABT-737 is a BH3 mimetic inhibitor of Bcl-xL, Bcl-2 and Bcl-w with EC50 of 78.7 nM, 30.3 nM and 197.8 nM in cell-free assays, respectively.
PC-28549	Obatoclax mesylate Bcl-2 inhibitor	Obatoclax mesylate (GX15-070) is a potent inhibitor of Bcl-2 family with IC50s of 1-7 uM for Bcl-2, Bcl-XL, Bcl-w, Bcl-B, Mcl-1 and Bfl-1.
PC-28265	BFL-1 inhibitor 20 Bfl-1 inhibitor	BFL-1 inhibitor 20 (Bfl-1-IN-6) is a potent, selective, covalent and orally bioavailable BFL-1 inhibitor with IC50 of 19 nM in TR-FRET assays, binds to Cys55 of BFL1.

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