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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Cathepsin-z-FA-FMK
z-FA-FMK

Chemical Structure : z-FA-FMK

CAS No.: 197855-65-5

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z-FA-FMK ((1S)-Z-FA-FMK)

货号: PC-25489Not For Human Use, Lab Use Only.

Z-FA-FMK ((1S)-Z-FA-FMK) is a potent cathepsin B and cathepsin L inhibitor, inhibits caspase activity in vitro and selectively inhibits recombinant effector caspases 2, -3, -6, and -7, but not caspases 8 and 10.

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10 mg ￥2380 In stock
25 mg ￥3980 In stock
50 mg ￥5980 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Z-FA-FMK ((1S)-Z-FA-FMK) is a potent cathepsin B and cathepsin L inhibitor, inhibits caspase activity in vitro and selectively inhibits recombinant effector caspases 2, -3, -6, and -7, but not caspases 8 and 10.

物理化学性质&存储条件

分子量 386.42
分子式 C21H23FN2O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Benzyl ((2S)-1-((4-fluoro-3-oxobutan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate

参考文献

1. Schotte P, et al. J Biol Chem. 2001 Jun 15;276(24):21153-7.

2. Lopez-Hernandez FJ, et, al. Mol Cancer Ther. 2003 Mar;2(3):255-63.

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