UB-MBX-46

Chemical Structure : UB-MBX-46

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货号: PC-25572Not For Human Use, Lab Use Only.

UB-MBX-46 is a potent, selective and allosteric antagonist of human P2X7 receptor (hP2X7R) antagonist with IC50 of 0.514 nM, 40.6 nM and 4.52 nM for human, rat and mouse P2X7R respectively.

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生物&药学活性

UB-MBX-46 is a potent, selective and allosteric antagonist of human P2X7 receptor (hP2X7R) antagonist with IC50 of 0.514 nM, 40.6 nM and 4.52 nM for human, rat and mouse P2X7R respectively.

物理化学性质&存储条件

分子量	358.91
分子式	C21H27ClN2O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	CC12C3(C)C(C2(C)C4)(C)CC4C(C3)(C(NNC5=C(Cl)C=CC=C5)=O)C1

参考文献

1. Oken AC, et al. Nat Commun. 2025 Sep 15;16(1):8283.

UB-MBX-46

生物&药学活性

物理化学性质&存储条件

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UB-MBX-46

生物&药学活性

物理化学性质&存储条件

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