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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-iGluR-Riluzole
Riluzole

Chemical Structure : Riluzole

CAS No.: 1744-22-5

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Riluzole (PK26124)

货号: PC-24489Not For Human Use, Lab Use Only.

Riluzole is an anticonvulsant agent and N-methyl-D-aspartate (NMDA) glutamate receptor blocker, also is a TPC2 activator, also inhibited Kv4.2, Kv4.2/DPP6, and Kv4.2/KChIP2c channels in a voltage-independent manner, also binds to the C-terminal domain of SARS-CoV-2 nucleocapsid protein and has antiviral activity.

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100 mg ￥580 In stock
250 mg ￥880 In stock
1 g ￥1480 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Riluzole is an anticonvulsant agent and N-methyl-D-aspartate (NMDA) glutamate receptor blocker, also is a TPC2 activator, also inhibited Kv4.2, Kv4.2/DPP6, and Kv4.2/KChIP2c channels in a voltage-independent manner, also binds to the C-terminal domain of SARS-CoV-2 nucleocapsid protein and has antiviral activity.

物理化学性质&存储条件

分子量 234.20
分子式 C8H5F3N2OS
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

6-(Trifluoromethoxy)benzo[d]thiazol-2-amine

参考文献

1. He Y, et al. Neuropharmacology. 2002 Feb;42(2):199-209.

2. Delgado-Ramírez M, et al. Eur J Pharmacol. 2025 Jan 5;986:177146.

3. Márquez-Moñino MÁ, et al. Structure. 2025 Jan 2;33(1):39-50.e6.

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