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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-P2X Receptor-PSB-2014
PSB-2014

Chemical Structure : PSB-2014

CAS No.: 439144-63-5

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PSB-2014 (PSB2014)

货号: PC-26166Not For Human Use, Lab Use Only.

PSB-2014 is a potent, selective and competitive P2X1 receptor (P2X1R) with IC50 of 23.1 nM, weakly inhibits P2X4, P2X7 and shows no activity against P2X2, P2X3 receptors.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PSB-2014 is a potent, selective and competitive P2X1 receptor (P2X1R) with IC50 of 23.1 nM, weakly inhibits P2X4, P2X7 and shows no activity against P2X2, P2X3 receptors.

物理化学性质&存储条件

分子量 383.67
分子式 C15H8ClF6NO2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(3,5-bis(trifluoromethyl)phenyl)-4-chloro-2-hydroxybenzamide

参考文献

1. Maoqun Tian, et al. J Med Chem. 2020 Jun 11;63(11):6164-6178.

2. Christa E Müller, et al. Recommended tool compounds and drugs for blocking P2X and P2Y receptors. Purinergic Signal. 2021 Dec;17(4):633-648.

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