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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-P2X Receptor-PSB-15417
PSB-15417

Chemical Structure : PSB-15417

CAS No.: 3047888-47-8

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PSB-15417 (PSB15417)

货号: PC-26162Not For Human Use, Lab Use Only.

PSB-15417 is a potent, specific P2X4 receptor (P2X4R) antagonist with IC50 of 21.9 nM and 37 nM for human and rat P2X4 receptor, shows limited activity against P2X1, P2X2, P2X3 and P2X7 receptors (All IC50>2 uM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PSB-15417 is a potent, specific P2X4 receptor (P2X4R) antagonist with IC50 of 21.9 nM and 37 nM for human and rat P2X4 receptor, shows limited activity against P2X1, P2X2, P2X3 and P2X7 receptors (All IC50>2 uM).

物理化学性质&存储条件

分子量 362.45
分子式 C20H18N4OS
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-(1H-indol-3-yl)-2-((2-methyl-5-(3-methyl-1,2,4-thiadiazol-5-yl)phenyl)amino)ethan-1-one

参考文献

1. Müller C. E.et al. Purinergic Signal. 2021, 17, 633–648.

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