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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-P2X Receptor-PSB-1011
PSB-1011

Chemical Structure : PSB-1011

CAS No.: 4499-01-8

PSB-1011

货号: PC-26167Not For Human Use, Lab Use Only.

PSB-1011 is a potent, moderately selective rat P2X2 receptor antagonist with IC50 of 79 nM, weakly inhibits P2X1 and P2X3 receptors and shows no activity against P2X4 and P2X7 receptors.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PSB-1011 is a potent, moderately selective rat P2X2 receptor antagonist with IC50 of 79 nM, weakly inhibits P2X1 and P2X3 receptors and shows no activity against P2X4 and P2X7 receptors.

物理化学性质&存储条件

分子量 681.38
分子式 C23H12Cl2N6Na2O8S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

sodium 1-amino-4-((3-((4,6-dichloro-1,3,5-triazin-2-yl)amino)-4-sulfonatophenyl)amino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate

参考文献

1. Baqi Y, et al. J Med Chem. 2011;54:817–830.

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