PLK3-IN-1

Chemical Structure : PLK3-IN-1

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货号: PC-27091Not For Human Use, Lab Use Only.

PLK3-IN-1 is a potent, isoform-selective PLK3 inhibitor with IC50 of 5 nM, has 1000- and 60-fold selectivity over PLK1 and PLK2.

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PLK3-IN-1 is a potent, isoform-selective PLK3 inhibitor with IC50 of 5 nM, has 1000- and 60-fold selectivity over PLK1 and PLK2.

分子量	500.58
分子式	C27H29FN8O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(2-{3-[(S)-1-methyl-3-piperidyl]-5-indolylamino}-5-fluoro-4-pyrimidinyl)-1-(2-pyridyl)-2-piperazinone

1. Jeremy L Yap, et al. ACS Med Chem Lett. 2026 May 13;17(6):1266-1274.