PLK1 inhibitor 31 | PLK1 inhibitor | Probechem Biochemicals

Chemical Structure : PLK1 inhibitor 31

CAS No.: 2622273-55-4

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PLK1 inhibitor 31 (PLK1-IN-4)

货号: PC-25788Not For Human Use, Lab Use Only.

PLK1 inhibitor 31 is a highly potent, selective polo-like kinase 1 (PLK1) inhibitor with IC50 of <0.5 nM, shows potent antiproliferative activity against a variety of cancer cell lines with IC50 of 11.1 nM for HCC cell line HepG2.

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2 mg	￥2780	In stock
5 mg	￥4580	In stock
10 mg	￥7280	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

PLK1 inhibitor 31 is a highly potent, selective polo-like kinase 1 (PLK1) inhibitor with IC50 of <0.5 nM, shows potent antiproliferative activity against a variety of cancer cell lines with IC50 of 11.1 nM for HCC cell line HepG2.

物理化学性质&存储条件

分子量	550.56
分子式	C24H25F3N6O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	methyl 3-((2-((1-(dimethylglycyl)-5-methoxyindolin-6-yl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)thiophene-2-carboxylate

参考文献

1. Zhou Deng, et al. Eur J Med Chem. 2020 Nov 15:206:112697.

PLK1 inhibitor 31 (PLK1-IN-4)

生物&药学活性

物理化学性质&存储条件

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PLK1 inhibitor 31 (PLK1-IN-4)

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物理化学性质&存储条件

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