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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-P2X Receptor-NF023
NF023

Chemical Structure : NF023

CAS No.:

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NF023 (NF023 hexasodium)

货号: PC-26164Not For Human Use, Lab Use Only.

NF023 hexasodium is a potent, selective and competitive P2X1 receptor (P2X1R) antagonist with IC50 of 0.21 uM (human P2X1), >100-fold selective over P2X3, P2X2, and P2X4 receptors.

规格 价格 库存 数量
5 mg ￥2980 In stock
10 mg ￥4580 In stock
25 mg ￥7580 In stock
50 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

NF023 hexasodium is a potent, selective and competitive P2X1 receptor (P2X1R) antagonist with IC50 of 0.21 uM (human P2X1), >100-fold selective over P2X3, P2X2, and P2X4 receptors.

物理化学性质&存储条件

分子量 1162.85
分子式 C35H20N4Na6O21S6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

sodium 8,8'-((3,3'-(carbonylbis(azanediyl))bis(benzoyl))bis(azanediyl))bis(naphthalene-1,3,5-trisulfonate)

参考文献

1. F Soto, et al. Neuropharmacology. 1999 Jan;38(1):141-9.

2. M Freissmuth, et al. Mol Pharmacol. 1996 Apr;49(4):602-11.

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