LY451395 | AMPAR PAM | Probechem Biochemicals

Chemical Structure : LY451395

CAS No.: 375345-95-2

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LY451395 (Mibampator, LY 451395, LY-451395)

货号: PC-42744Not For Human Use, Lab Use Only.

Mibampator (LY451395) is a potent, selective, and centrally active positive allosteric modulator of AMPAR-mediated neurotransmission, which increase ion channel flux in the presence of agonist by suppressing desensitization and/or deactivation of the receptors.

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5 mg	￥1980	In stock
10 mg	￥2980	In stock
25 mg	￥4880	In stock
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100 mg		Get quote

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生物&药学活性

Mibampator (LY451395) is a potent, selective, and centrally active positive allosteric modulator of AMPAR-mediated neurotransmission, which increase ion channel flux in the presence of agonist by suppressing desensitization and/or deactivation of the receptors.

物理化学性质&存储条件

分子量	438.6039
分子式	C21H30N2O4S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Propanesulfonamide, N-[(2R)-2-[4'-[2-[(methylsulfonyl)amino]ethyl][1,1'-biphenyl]-4-yl]propyl]-

参考文献

1. O'Neill MJ, et al. Curr Drug Targets CNS Neurol Disord. 2004 Jun;3(3):181-94.

2. Zmijewski M, et al. Drug Metab Dispos. 2006 Jun;34(6):925-31.

3. Malá H, et al. Behav Brain Res. 2012 Jan 1;226(1):18-25.

LY451395 (Mibampator, LY 451395, LY-451395)

生物&药学活性

物理化学性质&存储条件

参考文献

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LY451395 (Mibampator, LY 451395, LY-451395)

生物&药学活性

物理化学性质&存储条件

参考文献

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