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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-iGluR-JNJ-56022486
JNJ-56022486

Chemical Structure : JNJ-56022486

CAS No.: 2036082-79-6

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JNJ-56022486 (JNJ56022486)

货号: PC-28480Not For Human Use, Lab Use Only.

JNJ-56022486 is a potent, selective and orally active negative AMPA receptor modulator with Ki of 18 nM for transmembrane AMPA receptor regulatory protein γ8 (TARP-γ8, CACNG8).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

JNJ-56022486 is a potent, selective and orally active negative AMPA receptor modulator with Ki of 18 nM for transmembrane AMPA receptor regulatory protein γ8 (TARP-γ8, CACNG8).

物理化学性质&存储条件

分子量 283.72
分子式 C15H10ClN3O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(3-chloro-2-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)phenyl)acetonitrile

参考文献

1. Maher MP, et al. J Pharmacol Exp Ther. 2016 May;357(2):394-414.

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