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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-iGluR-Ifenprodil tartrate
Ifenprodil tartrate

Chemical Structure : Ifenprodil tartrate

CAS No.: 23210-58-4

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Ifenprodil tartrate (Ifenprodil hemitartrate)

货号: PC-43280Not For Human Use, Lab Use Only.

Ifenprodil tartrate is a potent, GluN2B-specific inhibitor NMDA receptor antagonist, specifically targets NR1A/NR2B receptors with IC50 of 0.34 uM, 400-fold selective over NR1A/NR2A receptors.

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100 mg ￥880 In stock
250 mg ￥1480 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Ifenprodil tartrate is a potent, GluN2B-specific inhibitor NMDA receptor antagonist, specifically targets NR1A/NR2B receptors with IC50 of 0.34 uM, 400-fold selective over NR1A/NR2A receptors.
Ifenprodil tartrate also inhibits GIRK channels, and interacts with alpha1 adrenergic, serotonin, and sigma receptors.

物理化学性质&存储条件

分子量 400.49
分子式 C21H27NO2 . 1/2C4H6O6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 500 mg/mL
Chemical Name/SMILES

1-Piperidineethanol, α-(4-hydroxyphenyl)-β-methyl-4-(phenylmethyl)-, (2R,3R)-2,3-dihydroxybutanedioate (2:1)

参考文献

1. Korinek M, et al. Steroids. 2011 Dec 11;76(13):1409-18.

2. Kobayashi T, et al. Neuropsychopharmacology. 2006 Mar;31(3):516-24.

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