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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-iGluR-GluN2B antagonist 22
GluN2B antagonist 22

Chemical Structure : GluN2B antagonist 22

CAS No.: 875898-41-2

GluN2B antagonist 22 (MK-22)

货号: PC-26197Not For Human Use, Lab Use Only.

GluN2B antagonist 22 (MK-22) is a highly potent, GluN2B (NR2B)-selective NMDA receptor antagonist with IC50/Ki of 1.0 nM and 0.88 nM, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

GluN2B antagonist 22 (MK-22) is a highly potent, GluN2B (NR2B)-selective NMDA receptor antagonist with IC50/Ki of 1.0 nM and 0.88 nM, respectively.

物理化学性质&存储条件

分子量 375.44
分子式 C20H21N7O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-((1S,3S)-3-(3-(4-methylbenzyl)-1,2,4-oxadiazol-5-yl)cyclopentyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

参考文献

1. Mark E Layton, et al. ACS Chem Neurosci. 2011 Jul 20;2(7):352-62.

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