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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-iGluR-Fanapanel
Fanapanel

Chemical Structure : Fanapanel

CAS No.: 161605-73-8

Fanapanel (ZK200775, MPQX)

货号: PC-25676Not For Human Use, Lab Use Only.

Fanapanel (ZK200775) is a highly selective AMPA/kainate antagonis with Ki values of 3.2 nM, 100 nM, and 8.5 μM against quisqualate, kainate, and NMDA, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Fanapanel (ZK200775) is a highly selective AMPA/kainate antagonis with Ki values of 3.2 nM, 100 nM, and 8.5 μM against quisqualate, kainate, and NMDA, respectively.

物理化学性质&存储条件

分子量 409.26
分子式 C14H15F3N3O6P
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

((7-Morpholino-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl)methyl)phosphonic acid

参考文献

1. Turski L, et al. ZK200775: a phosphonate quinoxalinedione AMPA antagonist for neuroprotection in stroke and trauma. Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10960-5.

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