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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-iGluR-EVT-101
EVT-101

Chemical Structure : EVT-101

CAS No.: 627525-33-1

EVT-101 (EVT101)

货号: PC-26196Not For Human Use, Lab Use Only.

EVT-101 is a highly potent, selective and orally active GluN2B antagonist with IC50 of 12 nM for GluN1/GluN2B.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

EVT-101 is a highly potent, selective and orally active GluN2B antagonist with IC50 of 12 nM for GluN1/GluN2B.

物理化学性质&存储条件

分子量 318.30
分子式 C16H13F3N4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-(3-(difluoromethyl)-4-fluorophenyl)-3-((2-methyl-1H-imidazol-1-yl)methyl)pyridazine

参考文献

1. Fernandes A, et al. Eur J Pharmacol. 2015 Nov 5;766:1-8.

2. Stroebel D, et al. Mol Pharmacol. 2016 May;89(5):541-51.

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