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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-iGluR-EU93-31
EU93-31

Chemical Structure : EU93-31

CAS No.: 457897-98-2

EU93-31 (Compound 93-31)

货号: PC-26194Not For Human Use, Lab Use Only.

EU93-31 is a potent, pH-sensitive GluN2B-selective antagonist of NMDA receptor with IC50 of 0.19 uM (GluN1/GluN2B, pH=6.9) and 1.8 uM (GluN1/GluN2B, pH=7.6).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

EU93-31 is a potent, pH-sensitive GluN2B-selective antagonist of NMDA receptor with IC50 of 0.19 uM (GluN1/GluN2B, pH=6.9) and 1.8 uM (GluN1/GluN2B, pH=7.6).

物理化学性质&存储条件

分子量 489.45
分子式 C22H30Cl2N2O4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-N-(4-(3-(butyl(3,4-dichlorophenethyl)amino)-2-hydroxypropoxy)phenyl)methanesulfonamide

参考文献

1. Yuan H, et al. Neuron. 2015 Mar 18;85(6):1305-1318.

2. Harris LD, et al. ACS Chem Neurosci. 2023 Mar 1;14(5):917-935.

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