DQP-997-74

Chemical Structure : DQP-997-74

CAS No.: 2377187-09-0

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货号: PC-21031Not For Human Use, Lab Use Only.

DQP-997-74 is a potent, selective GluN2C- and GluN2D-containing NMDARs negative allosteric modulator with IC50 of 0.35 and 0.13 uM, respectively, exhibits >100-fold over GluN2A- and GluN2B-containing receptors.

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2 mg	￥2480	In stock
5 mg	￥4280	In stock
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DQP-997-74 is a potent, selective GluN2C- and GluN2D-containing NMDARs negative allosteric modulator with IC50 of 0.35 and 0.13 uM, respectively, exhibits >100-fold over GluN2A- and GluN2B-containing receptors.

物理化学性质&存储条件

分子量	570.37
分子式	C28H19Cl2F2N3O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(5-(4-chlorophenyl)-3-(4-(4-chlorophenyl)-2-oxo-1,2-dihydroquinolin-3-yl)-4,5-dihydro-1H-pyrazol-1-yl)-3,3-difluoro-4-oxobutanoic acid

参考文献

1. Michael P. D'Erasmo, et al. ACS Chemical Neuroscience. August 11, 2023.

DQP-997-74

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物理化学性质&存储条件

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DQP-997-74

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物理化学性质&存储条件

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