CP-465022 |CAS:199655-36-2 Probechem Biochemicals

Chemical Structure : CP-465022

CAS No.: 199655-36-2

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CP-465022 (CP465022)

货号: PC-61727Not For Human Use, Lab Use Only.

CP-465022 is a potent, selective, noncompetitive AMPA receptor (AMPAR) antagonist with IC50 of 36 nM.

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5 mg	￥980	In stock
10 mg	￥1580	In stock
25 mg	￥2780	In stock
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100 mg		Get quote

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生物&药学活性

CP-465022 is a potent, selective, noncompetitive AMPA receptor (AMPAR) antagonist with IC50 of 36 nM.
CP-465022displays selectivity over kainate and NMDA receptors.
CP-465022 inhibits AMPA receptor-mediated currents in rat cortical neurons with IC50 of 25 nM.
CP-465022 displays potent anticonvulsant activity in vivo.

物理化学性质&存储条件

分子量	462.95
分子式	C26H24ClFN4O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(2-Chlorophenyl)-2-[2-[6-[(diethylamino)methyl]-2-pyridinyl]ethenyl]-6-fluoro-4(3H)-quinazolinone

参考文献

1. Menniti FS, et al. Mol Pharmacol. 2000 Dec;58(6):1310-7.

2. Welch WM, et al. Bioorg Med Chem Lett. 2001 Jan 22;11(2):177-81.

3. Lazzaro JT, et al. Neuropharmacology. 2002 Feb;42(2):143-53.

CP-465022 (CP465022)

生物&药学活性

物理化学性质&存储条件

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CP-465022 (CP465022)

生物&药学活性

物理化学性质&存储条件

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