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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-iGluR-CGP-78608 hydrochloride
CGP-78608 hydrochloride

Chemical Structure : CGP-78608 hydrochloride

CAS No.: 1135278-54-4

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CGP-78608 hydrochloride (CGP78608 hydrochloride)

货号: PC-26281Not For Human Use, Lab Use Only.

CGP 78608 hydrochloride is a highly potent and selective antagonist of GluN1/GluN3 NMDAR, antagonizes GluN1/GluN2 receptors, acts as an ultra-potent and powerful potentiator of GluN1/GluN3A receptors.

规格 价格 库存 数量
5 mg ￥3280 In stock
10 mg ￥5280 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CGP 78608 hydrochloride is a highly potent and selective antagonist of GluN1/GluN3 NMDAR, antagonizes GluN1/GluN2 receptors, acts as an ultra-potent and powerful potentiator of GluN1/GluN3A receptors.

物理化学性质&存储条件

分子量 414.58
分子式 C11H14BrClN3O5P
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Phosphonic acid, P-[(1S)-1-[[(7-bromo-1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl]amino]ethyl]-, hydrochlorid

参考文献

1. Hilgier W, et al. Brain Res. 2004 Jul 23;1015(1-2):186-8.

2. Gabra BH, et al. J Pharmacol Exp Ther. 2007 Jul;322(1):186-94.

3. Grand T, et al. Nat Commun. 2018 Nov 13;9(1):4769.

4. Auberson YP, et al. Bioorg. Med. Chem. Lett. 1999;9:249–254.

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