| Cat. No. |
Product Name |
Information |
| PC-62447 |
Cardionogen 1
Wnt inhibitor
|
Cardionogen 1 (CDNG1) is a small molecule that promotes cardiomyocyte generation by modulating Wnt signaling. |
| PC-62446 |
Cardionogen 2
Wnt inhibitor
|
Cardionogen 2 (CDNG2) is a small molecule that promotes cardiomyocyte generation by modulating Wnt signaling. |
| PC-62039 |
Wntepane 1
Vangl1 modulator
|
Wntepane 1 is a small-molecule activator of the Wnt pathway that modulates the van-Gogh-like receptor 1 (Vangl1), activates Wnt signaling with EC50 of 1.8 uM in the reporter gene assay. |
| PC-61759 |
Foxy-5
Wnt5A agonist
|
Foxy-5 (formyl-Met-Asp-Gly-Cys-Glu-Leu) is a Wnt5A mimicking hexapeptide that inhibits breast cancer metastasis in vivo by targeting cell motility. |
| PC-70264 |
QS-11
ARFGAP1 inhibitor
|
QS-11 (QS11) is a small molecule inhibitor of GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) with Kd of 620 nM, synergizes the Wnt/beta-catenin signaling. |
| PC-70223 |
Prodigiosin
Wnt/β-catenin inhibitor
|
Prodigiosin is a natural red pigment produced by numerous bacterial species, has exhibited promising anticancer activity. |
| PC-45698 |
JW74
Wnt inhibitor
|
JW74 is an efficient and specific inhibitor of the canonical Wnt signaling with IC50 of 0.79 uM in ST-Luc assay. |
| PC-45774 |
BML-284
Wnt/β-catenin inhibitor
|
BML-284 (AMBMP) is a potent selective, and cell-permeable canonical Wnt/β-catenin pathway activator with EC50 of 0.7 uM (induces beta-catenin- and TCF-dependent transcriptional activity). |
| PC-42926 |
IWR-1
Wnt inhibitor
|
IWR-1 is a potent inhibitor of Wnt signaling with EC50 of 0.2 uM. |
| PC-44658 |
FH535
Wnt inhibitor
|
FH535 is a potent, dual PPARγ/δ antagonist that is able to inhibit GRIP1 and β-catenin recruitment, inhibits the Wnt/β-catenin pathway. |
| PC-26107 |
SLD1121
Wnt/β-catenin agonist
|
SLD1121(SLD-1121) is a small molecule agonist of Wnt/β-catenin signaling pathway with EC50 of 0.21 uM for LRP6-mediated Wnt activation, interacts with the intracellular domain of LRP6 (Kd=7.49 nM, LRP6-ICD domain), stabilizes LRP6, and accelerates its nuclear translocation. |
| PC-25594 |
IWP-3
Wnt inhibitor, CK1γ3 inhibitor
|
IWP-3 is a potent, small molecule inhibitor of Wnt production with IC50 of 40 nM, inhibits Porcupine (Porcn) function thereby blocking palmitoylation of Wnt proteins, inhibits CK1γ3 and CK1ε, does not inhibit CK1α. |
