| Cat. No. |
Product Name |
Information |
| PC-42450 |
Cediranib
VEGFR inhibitor
|
Cediranib (AZD2171) is a highly potent, orally bioavailable, pan-VEGFR inibitor with IC50 of 1, 5, 3 nM for VEGFR1, 2, 3, respectively. |
| PC-42759 |
Tivozanib
VEGFR inhibitor
|
Tivozanib (AV951) is a highly potent inhibitor of pan-VEGFR with IC50s of 60/6.5/15 nM for VEGFR1/2/3. |
| PC-42534 |
Brivanib
FGFR/VEGFR inhibitor
|
Brivanib (BMS540215) is a potent, dual inhibitor of VEGFR2 and FGFR1 with IC50 of 25 nM and 148 nM respectively. |
| PC-42623 |
SU14813 maleate
Multikinase inhibitor
|
SU14813 maleate is a broad-spectrum RTKs inhibitor with IC50 ranging from 2 to 50 nM for VEGFR-1, VEGFR-2, PDGFRs, KIT, FLT3, and CSF1R/FMS. |
| PC-42622 |
SU14813
Multikinase inhibitor
|
SU14813 is a potent, broad-spectrum RTKs inhibitor with IC50 ranging from 2 to 50 nM for VEGFR-1, VEGFR-2, PDGFRs, KIT, FLT3, and CSF1R/FMS. |
| PC-28597 |
ZM323881 hydrochloride
VEGFR2 inhibitor
|
ZM323881 hydrochloride is a potent, specific VEGFR2 inhibitor with IC50 of <2 nM, shows high selectivity over other receptor tyrosine kinases, including VEGFR1. |
| PC-28596 |
ZM323881
VEGFR2 inhibitor
|
ZM323881 is a potent, specific VEGFR2 inhibitor with IC50 of <2 nM, shows high selectivity over other receptor tyrosine kinases, including VEGFR1. |
| PC-27814 |
ATWLPPR peptide TFA
NRP-1 inhibitor
|
ATWLPPR peptide TFA (A7R, Ala-Thr-Trp-Leu-Pro-Pro-Arg) is a specific NRP-1 (Neuropilin 1, NRP1) inhibitor and effective antagonist of the VEGF165 binding to NRP-1 with IC50 of 5.9 uM blocks vascular endothelial growth factor (VEGF)-mediated angiogenesis. |
| PC-25744 |
EG01449
NRP1 inhibitor
|
EG01449 is a specific, small molecule neuropilin-1 (NRP1) antagonist, inhibits bt-VEGFA to NRP1 b1 domain with IC50 of 362 nM, and SPR KD of 0.6 uM for binding to NRP1 b1 domain. |
| PC-25522 |
TAK-593
VEGFR2 inhibitor
|
TAK-593 is a potent, selective and ATP-competitive inhibitor of tyrosine kinases VEGFR and PDGFR with IC50s of 3.2, 0.95, 1.1, 4.3 and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα and PDFGRβ, respectively. |
| PC-25098 |
Taligantinib
Tyrosine kinase inhibitor
|
Taligantinib is a potent tyrosine kinase (such as VEGFR-2 and c-Met) inhibitor. |
| PC-24617 |
Tie2 inhibitor compound 5
Tie2 inhibitor
|
Tie2 inhibitor compound 5 (Tie2-IN-1) is a potent, selective Tie2 kinase inhibitor with IC50 of 250 nM, >200-fold selective over p38. |
