| Cat. No. |
Product Name |
Information |
| PC-22046 |
M435-1279
UBE2T inhibitor
|
M435-1279 is a small molecule inhibitor of UBE2T inhibitor with binding KD of 50.5 uM in MST assay, inhibits the Wnt/β-catenin signaling pathway hyperactivation through blocking UBE2T-mediated degradation of RACK1. |
| PC-21311 |
HA-9104
UBE2F inhibitor
|
HA-9104 is a specific small molecule inhibitor of E2 conjugating enzyme UBE2F with IC50 of 33.29 uM for inhibition of cullin-5 neddylation, abrogates UBE2F-NEDD8 thioester formation and inhibits cullin-5 neddylation. |
| PC-20652 |
UM130646
UBCH10 inhibitor
|
UM130646 (UM 130646) is a specific small molecule E2 enzyme UBCH10 inhibitor with IC50 of 20.3 uM in TR-FRET UBCH10 autoubiquitination assays, inhibits UBCH10 E2 activity and antagonizes APC/C-mediated substrate degradation. |