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首页-小分子抑制剂&激动剂-Proteasome/Ubiquitin-Ubiquitin-conjugating Enzyme (E2)

Request The Product List ofUbiquitin-conjugating Enzyme (E2) Ubiquitin-conjugating Enzyme (E2)

Cat. No. Product Name Information
PC-22046

M435-1279

UBE2T inhibitor

M435-1279 is a small molecule inhibitor of UBE2T inhibitor with binding KD of 50.5 uM in MST assay, inhibits the Wnt/β-catenin signaling pathway hyperactivation through blocking UBE2T-mediated degradation of RACK1.
PC-21311

HA-9104

UBE2F inhibitor

HA-9104 is a specific small molecule inhibitor of E2 conjugating enzyme UBE2F with IC50 of 33.29 uM for inhibition of cullin-5 neddylation, abrogates UBE2F-NEDD8 thioester formation and inhibits cullin-5 neddylation.
PC-20652

UM130646

UBCH10 inhibitor

UM130646 (UM 130646) is a specific small molecule E2 enzyme UBCH10 inhibitor with IC50 of 20.3 uM in TR-FRET UBCH10 autoubiquitination assays, inhibits UBCH10 E2 activity and antagonizes APC/C-mediated substrate degradation.

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