| Cat. No. |
Product Name |
Information |
| PC-60888 |
PD166285
Src/Wee1/Myt1 inhibitor
|
PD166285 (PD-166285, PD0166285) is a broad-spectrum receptor tyrosine kinase (RTK) inhibitor that inhibits PDGFR-β, EGFR, and FGFR1 and c-Src with IC50 of 7-85 nM, also inhibits the checkpoint kinases Wee1 and Myt1. |
| PC-60584 |
JP-153
FAK-paxillin inhibitor
|
JP-153 (JP153) is a selective FAK-paxillin durotaxis inhibitor, targets the Src-FAK-Paxillin signaling, inhibits Src-dependent phosphorylation of paxillin (Y118) and downstream activation of Akt (S473) in RECs. |
| PC-70182 |
TX-1123
Src inhibitor
|
TX-1123 is a tyrphostin AG17 analog that exihibits potent Src kinase inhibitory activity with IC50 of 2.2 uM. |
| PC-70102 |
Damnacanthal
p56lck inhibitor
|
Damnacanthal is a highly potent, selective inhibitor of p56 lck tyrosine kinase with IC50 of 17 nM for inhibition of p56lck autophosphorylation. |
| PC-42433 |
TG 100801
Src inhibitor
|
The prodrug of TG 100572, a potent, dual receptor tyrosine kinase/Src kinase inhibitor with IC50 of 2-16 nM for VEGFR, FGFR and PDGFR, 0.1-5 nM for Src family. |
| PC-42561 |
PD173955
Src inhibitor
|
PD173955 is a potent, selective, ATP-competitive Src family kinases inhibitor with IC50 of 22 nM for Src. |
| PC-42475 |
Saracatinib
Src/Abl inhibitor
|
Saracatinib (AZD0530) is a potent, highly selective, orally available, dual Src/Abl kinase inhibitor with IC50 of 2.7, 4, 4 and 30 nM for c-Src, Yes, Lck and Abl, respectively. |
| PC-42432 |
TG 100572 hydrochloride
Src inhibitor
|
TG100572 hydrochloride is a potent, dual receptor tyrosine kinase/Src kinase inhibitor with IC50 of 2-16 nM for VEGFR, FGFR and PDGFR, 0.1-5 nM for Src family. |
| PC-42431 |
TG 100572
Src inhibitor
|
TG100572 is a potent, dual receptor tyrosine kinase/Src kinase inhibitor with IC50 of 2-16 nM for VEGFR, FGFR and PDGFR, 0.1-5 nM for Src family. |
| PC-42690 |
Lck inhibitor 2
Lck inhibitor
|
Lck inhibitor 2 uis a potent tyrosine kinases inhibitor with IC50 of 13/9/3/26/2 nM for Lck/Btk/Lyn/Syk/Txk. |
| PC-43793 |
1-Naphthyl PP1 hydrochloride
Src inhibitor
|
1-Naphthyl PP1 hydrochloride is a potent Src family kinases with IC50 of 1.0/0.6/0.6 uM for v-Sr/c-Fyn/c-Abl. |
| PC-43792 |
1-Naphthyl PP1
Src inhibitor
|
1-Naphthyl PP1 (1-NA-PP1) is a potent Src family kinases with IC50 of 1.0/0.6/0.6 uM for v-Sr/c-Fyn/c-Abl. |
