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首页-小分子抑制剂&激动剂-PI3K/Akt/mTOR Pathway-PIKfyve

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Cat. No. Product Name Information
PC-23927

PIKfyve inhibitor 40

PIKfyve inhibitor

PIKfyve inhibitor 40 is a potent, selective, second-generation inhibitor of PIKfyve with enzyme IC50 of 0.6 nM, and 0.35 nM in NanoBRET assays.
PC-22798

UNI418

PIKfyve/PIP5K1C inhibitor

UNI418 (UNI-418) is a potent, specific dual PIKfyve and PIP5K1C inhibitor with IC50 of 60.7 nM/60.1 nM for PIP5K1B/PIP5K1C, Kd of 0.78 nM for PIKfyve (100% inhibition at 1 uM), inhibits UNI418 inhibits SARS-CoV-2 infection of Vero cells with IC50 of 1.4 uM.

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