| Cat. No. |
Product Name |
Information |
| PC-45978 |
Naltrexone hydrochloride
Opioid receptor antagonist
|
Naltrexone hydrochloride is a potent, competitive antagonist for μ, κ, δ, and σ-opioid receptors with Ki of 0.0825 nM, 0.509 nM, and 8.02 nM, for MOR, KOR, and DOR, respectively. |
| PC-45960 |
Naltrexone methylbromide
Opioid receptor antagonist
|
Naltrexone methylbromide (Naltrexone methylbromide) is a peripherally-acting μ-opioid antagonist that acts to reverse some of the side effects of opioid drugs such as constipation without affecting analgesia or precipitating withdrawals. |
| PC-45285 |
Meptazinol
MOR agonist
|
Meptazinol (IL-22811, WY-22811) is a partial µ-opioid receptor (MOR) agonist. |
| PC-42615 |
JDTic dihydrochloride
KOR antagonist
|
JDTic dihydrochloride is a highly potent and selective kappa Opioid receptor (KOR) antagonist with Ki of 0.3 nM. |
| PC-42614 |
JDTic
KOR antagonist
|
JDTic is a highly potent and selective kappa opioid receptor (KOR) antagonist with Ki of 0.3 nM. |
| PC-47491 |
Dynorphin A(1-13)
Neurolysin inhibitor, KOR agonist
|
Dynorphin A(1-13) is a potent, competitive peptidie inhibitor of Neurolysin (Nln) with IC50 of 1.2 uM, also is a kappa receptor agonist binds to human kappa opioid receptor (KOR) with Ki of 200 nM. |
| PC-27320 |
BPR1M492
MOR agonist
|
BPR1M492 is a potent, selective, fast-acting μ-opioid receptor (MOR) agonist with EC50 of 4 nM in FLIPR Ca2+ assays, Emax=92.7%. |
| PC-27173 |
nor-Binaltorphimine dihydrochloride
KOR antagonist
|
nor-Binaltorphimine dihydrochloride (Nor-BNI, Norbinaltorphimine) is a potent, selective, long-acting competitive κ-opioid receptor (KOR) antagonist, blocks KOR-mediated analgesic effects, and inhibits butorphanol-induced changes in κ-opioid receptor binding kinetics, desensitization and down-regulation. |
| PC-27172 |
nor-Binaltorphimine
KOR antagonist
|
nor-Binaltorphimine (Nor-BNI, Norbinaltorphimine) is a potent, selective, long-acting competitive κ-opioid receptor (KOR) antagonist, blocks KOR-mediated analgesic effects, and inhibits butorphanol-induced changes in κ-opioid receptor binding kinetics, desensitization and down-regulation. |
| PC-27171 |
CTAP TFA
MOR antagonist
|
CTAP TFA is a potent, highly selective, and BBB-penetrant μ opioid receptor (MOR) antagonist with IC50 of 3.5 nM ,> 1200-fold selectivity over δ opioid receptor ( MOR, IC50=4500 nM) and somatostatin receptors. |
| PC-27170 |
CTAP
MOR antagonist
|
CTAP is a potent, highly selective, and BBB-penetrant μ opioid receptor (MOR) antagonist with IC50 of 3.5 nM ,> 1200-fold selectivity over δ opioid receptor ( MOR, IC50=4500 nM) and somatostatin receptors. |
| PC-27169 |
SLL-022CCP
KOR agonist
|
SLL-022CCP is a potent, selective κ-opioid receptor (KOR) agonist with EC50 of 0.002 nM for inhibiting cAMP production, exhibits high receptor subtype selectivity over μ-opioid receptor (MOR, EC50=1.6 nM) and δ-opioid receptor (DOR, EC50=30.0 nM). |
