| Cat. No. |
Product Name |
Information |
| PC-62229 |
iNOS inhibitor 12
iNOS inhibitor
|
iNOS inhibitor 12 is a potent, highly selective iNOS inhibitor with IC50 of 79 nM, dispalys almost 100-fold selectivity over eNOS and nNOS. |
| PC-61062 |
nNOS-IN-25
nNOS inhibitor
|
nNOS-IN-25 is a potent, selective cell permeable neuronal nitric oxide synthase (nNOS) inhibitor with Ki of 30 nM. |
| PC-60993 |
ASP9853
iNOS inhibitor
|
ASP9853 is a potent, orally active iNOS inhibitor (IC50=10 nM, NO release DLD-1 cells) that prevents dimerization of iNOS, but has no effect on the expression or enzyme activity of iNOS. |
| PC-70228 |
1400W dihydrochloride
iNOS inhibitor
|
1400W dihydrochloride is a potent, selective inhibitor of iNOS with Ki of 7 nM. |
| PC-45544 |
L-NAME hydrochloride
NOS inhibitor
|
L-NAME hydrochloride is a widely used inhibitor of NO synthase (NOS) with IC50 of 70 uM for purified brain NOS. |
| PC-42163 |
IC87201
PSD-95/nNOS inhibitor
|
IC87201 (IC 87201) is a small molecule inhibitor of PSD-95/nNOS interaction with IC50 of 31 uM, without inhibiting nNOS catalytic activity. |
| PC-42162 |
ZL006
PSD95-nNOS inhibitor
|
ZL006 (ZL 006, ZL006) is a brain penetrant small molecule inhibitor of PSD-95/nNOS interaction that prevents glutamate-induced excitotoxicity and cerebral ischemic damage in vivo. |
| PC-25145 |
SCR-4026
nNOS-PSD95 inhibitor
|
SCR-4026 is a small molecule inhibitor of nNOS-PSD95 interaction, disrupts nNOS-PSD-95 association with an IC50 of 6.3 μM in vitro. |
| PC-25066 |
Lubeluzole dihydrochloride
NOS inhibitor
|
Lubeluzole dihydrochloride is a neuroprotective agent displaying antimyotonic activity, inhibits glutamate-stimulated guanosine 3',5'-cyclic monophosphate production with IC50 of 37 nM, inhibits the glutamate-activated nitric oxide synthase pathway. |
| PC-25065 |
Lubeluzole
NOS inhibitor
|
Lubeluzole is a neuroprotective agent displaying antimyotonic activity, inhibits glutamate-stimulated guanosine 3',5'-cyclic monophosphate production with IC50 of 37 nM, inhibits the glutamate-activated nitric oxide synthase pathway. |
| PC-23980 |
MAC-3-190
nNOS inhibitor
|
MAC-3-190 is a potent, selective inhibitor of neuronal nitric oxide synthase (nNOS), inhibits the growth of metastatic melanoma, glioblastoma, and hepatocellular carcinoma in vitro and in vivo. |
| PC-23979 |
HH044
nNOS inhibitor
|
HH044 is a potent, selective inhibitor of neuronal nitric oxide synthase (nNOS) with Ki of 5 nM, >250-fold selective over iNOS and eNOS. |
