| Cat. No. |
Product Name |
Information |
| PC-60862 |
Quininib
CysLT1/CysLT2 antagonist
|
Quininib is a potent inhibitor of developmental angiogenesis in the zebrafish eye, and a cysteinyl leukotriene 1 and 2 receptor (CysLT1 and 2) antaognist with IC50 of 1.2 and 52 uM, respectively. |
| PC-45294 |
Zafirlukast
CysLT1 antagonist
|
Zafirlukast (ICI-204219) is a potent, selective, orally active cysteinyl leukotriene 1 (CysLT1) receptor antagonist with IC50 of 14 nM in cell-based calcium mobilization assays. |
| PC-45775 |
MK-571 sodium salt
LTD4 inhibitor
|
MK-571 sodium is a potent and specific LTD4 receptor antagonist with Ki of 0.22 nM. |
| PC-25787 |
CP105696
BLT1 antagonist
|
CP105696 (CP-105696) is a highly potent, selective leukotriene B4 (LTB4) receptor 1 (BLT1) antagonist, inhibits binding of [3H]LTB4 to whole human neutrophils with IC50 of 5.6 nM, inhibits LTB4 induced chemotaxis of human neutrophils with IC50 of 5.2 nM. |
| PC-23852 |
CAY10583
BLT2 agonist
|
CAY10583 is a potent and selective leukotriene B4 receptor type 2 (BLT2) agonist, inhibits LTB4 binding to BLT2 with IC50 of 20 nM, but not BLT1. |
| PC-23851 |
T-10430
BLT2 agonist
|
T-10430 is a potent and selective agonist of leukotriene B4 receptor 2 (BLT2) with EC50 of 0.51 nM in cAMP assays. |
| PC-21194 |
U75302
LTB4 receptor 1 inhibitor
|
U75302 is a specific leukotriene B4 receptor 1 (LTB4 receptor 1, BLTR1, BLT1) inhibitor, effectively block LTB4 responses. |