IRE1 (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-25597	IA107 IRE1α inhibitor	IA107 is a potent and selective inositol-requiring enzyme 1 alpha (IRE1α) inhibitor, inhibitsIRE1α and phosphorylated IRE1α RNase activity in FRET assay with IC50 of 16 nM and 9 nM, respectively.
PC-23681	1ACTA IRE1α S-nitrosylation inhibitor	1ACTA is a specific small molecule inhibitor of IRE1α S-nitrosylation, selectively prevents the NO-induced reduction of RNase activity.
PC-22296	IRE1α inhibitor 16 IRE1α inhibitor	IRE1α inhibitor 18 is a potent, selective and allosteric inhibitor of IRE1α endonuclease activity with enzyme IC50 of 13 nM, cellular IRE1α IC50 of 99 nM in XBP1-Luc cellular assays.
PC-22293	G-5758 IRE1α inhibitor	G-5758 (G5758) is a potent and selective, orally active IRE1α inhibitor with IC50 of 0.27 nM in HTRF IRE1α binding assays, inhibits IRE1α-Rnase with IC50 of 4.3 nM.

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