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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-IRE1

Request The Product List ofIRE1 IRE1

Cat. No. Product Name Information
PC-23681

1ACTA

IRE1α S-nitrosylation inhibitor

1ACTA is a specific small molecule inhibitor of IRE1α S-nitrosylation, selectively prevents the NO-induced reduction of RNase activity.
PC-23415

IXA4

IRE1/XBP1s activator

IXA4 is a specific activator of IRE1/XBP1s signalling activator, promotes IRE1-dependent XBP1 splicing, selective activates the IRE1/XBP1s signaling.
PC-22296

IRE1α inhibitor 16

IRE1α inhibitor

IRE1α inhibitor 18 is a potent, selective and allosteric inhibitor of IRE1α endonuclease activity with enzyme IC50 of 13 nM, cellular IRE1α IC50 of 99 nM in XBP1-Luc cellular assays.
PC-22293

G-5758

IRE1α inhibitor

G-5758 (G5758) is a potent and selective, orally active IRE1α inhibitor with IC50 of 0.27 nM in HTRF IRE1α binding assays, inhibits IRE1α-Rnase with IC50 of 4.3 nM.

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