| Cat. No. |
Product Name |
Information |
| PC-22268 |
BIO-8169
IRAK4 inhibitor
|
BIO-8169 is a highly potent, selective, brain-penetrant and oral bioavailable IRAK4 inhibitor with IC50 of 0.23 nM, potently inhibits R848 stimulated IL-1β production with IC50 of 246 nM in HWB assays. |
| PC-22241 |
DW18134
IRAK4 inhibitor
|
DW18134 is a potent, selective IRAK4 kinase inhibitor with IC50 of 11.2 nM, inhibits the IRAK4-induced activation of NF-κB signaling. |
| PC-21921 |
BIO-7488
IRAK4 inhibitor
|
BIO-7488 (BIO7488) is the first potent, selective, and CNS-penetrant IRAK4 inhibitor with IC50 of 0.5 nM (1 mM ATP). |