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首页-小分子抑制剂&激动剂-Immunology/Inflammation-IRAK

Request The Product List ofIRAK IRAK

Cat. No. Product Name Information
PC-26786

UR241-2

IRAK4 inhibitor

UR241-2 is a potent and selective IRAK4 inhibitor with IC50 of 1.93 nM in HotSpot Kinase assays, inhibits NF-κβ nuclear translocation and blocks IL-1β–induced IRAK4 phosphorylation.
PC-24961

Nacresertib

IRAK4 inhibitor

Nacresertib is a potent, selctive IRAK4 inhibitor with IC50 of 6.0 nM, >500-fold selective over IRAK1
PC-22315

JH-I-25

IRAK4 inhibitor

JH-I-25 is a potent, selective and orally bioavailable interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor with IC50 of 20 nM.
PC-22241

DW18134

IRAK4 inhibitor

DW18134 is a potent, selective IRAK4 kinase inhibitor with IC50 of 11.2 nM, inhibits the IRAK4-induced activation of NF-κB signaling.

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