| Cat. No. |
Product Name |
Information |
| PC-22186 |
GS-8873
HBsAg inhibitor
|
GS-8873 is a potent, orally bioavailable inhibitor of HBV surface antigen (HBsAg) with EC50 of 4 nM in HepG2-NTCP assays, via inhibition of the human poly(A) polymerases PAPD5/7, promoting destabilization and degradation of HBV mRNA. |
| PC-21756 |
SAG-524
HBV inhibitor
|
SAG-524 (SAG524) is a potent and orally bioavailable small molecule inhibitor of HBV replication, reduces HBsAg and HBV-DNA (IC50 = 0.92 nM and 1.4 nM) by destabilizing HBV-RNA. |
| PC-20678 |
AB-836
HBV capsid inhibitor
|
AB-836 is a next generation oral hepatitis B virus (HBV) capsid inhibitor with HepDE19 EC50 of 10 nM, interacts with HBV core protein and demonstrates robust antiviral activity. |
| PC-20253 |
Bersacapavir
HBV capsid inhibitor
|
Bersacapavir (JNJ-56136379, JNJ-6379) is a potent HBV capsid assembly modulator, JNJ-6379 specifically and potently inhibits HBV replication with EC50 of 54 nM (HepG2.117 cells). |
| PC-20252 |
Bulevirtide
HBV entry inhibitor
|
Bulevirtide (Myrcludex B, MyrB) is an acylated peptide derived from the large HBV envelope protein, inhibits virus entry and infection. |
| PC-20059 |
Neracorvir
HBV inhibitor
|
Neracorvir is a potent anti-HBV agent, targets HBV surface antigen. |
| PC-49649 |
E-CFCP
HBV inhibitor
|
E-CFCP is a novel long-acting nucleotide reverse transcriptase inhibitor (NRTI) against HBV, shows potent activity against HBV WTD1 and HBV WTC2 with IC50 of 1.8 and 0.7 nM, respectively. |
| PC-49567 |
Vebicorvir
HBV inhibitor
|
Vebicorvir (ABI-H0731) is a first-generation hepatitis B virus (HBV) core protein inhibitor, exhibits selective inhibition of HBV DNA replication with EC50 from 173 nM to 307 nM. |
| PC-49553 |
Nitazoxanide
HBx-DDB1 inhibitor
|
Nitazoxanide (NTX) is a thiazolide anti-infective agent that efficiently inhibits the HBV regulatory protein X (HBx)-DDB1 protein interaction, exhibits potent inhibition of both HBV and HCV replication. |
| PC-49333 |
GST-HG131
HBV antigen inhibitor
|
GST-HG131 is a specific small molecule HBV antigen inhibitor, exhibits excellent and specific HBV antigens inhibition with EC50 of 28.2 nM (HBsAg) and 16.0 nM (HBeAg), respectively. |
| PC-47007 |
DF-006
ALPK1 agonist
|
DF-006 is a small molecule, orally active Alpha-kinase 1 (ALPK1) agonist, activates ALPK1 and stimulates host innate immunity locally in liver, DF-006 enacts potent anti-HBV responses in mouse models of HBV and in primary human hepatocytes. |
| PC-38680 |
Firzacorvir
HBV inhibitor
|
Firzacorvir (ABI-H2158) is a novel potent HBV core inhibitor structurally distinct from other core inhibitors, ABI-H2158 is a pan-genotypic HBV inhibitor with EC50s ranging from 7.1 to 22 nM across HBV genotypes A-E. |
