| Cat. No. |
Product Name |
Information |
| PC-25101 |
AM-2-19
Antifungal
|
AM-2-19 (Turletricin, SF001) is an ergosterol-extracting polyene antifungal agent. |
| PC-24877 |
CMLD009688
F. graminearum inhibitor
|
CMLD009688 is a growth inhibitor of Fusarium graminearum with MIC of 12.5-50 uM, acts as a cationic amphiphilic compound to inhibit F. graminearum conidial germination in a fungicidal manner. |
| PC-24828 |
Micafungin
Antifungal, UBE2M inhibitor
|
Micafungin (FK463) is an echinocandin antifungal drug which can inhibit 1,3-beta-D-glucan synthase, inhibits the production of 1,3-β-D-glucan in fungal cell walls, acts as a neddylation inhibitor that targets Ubiquitin-conjugating enzyme 2M (UBE2M). |
| PC-24827 |
Collismycin A
Iron chelator
|
Collismycin A (CMA, SF2738A) is a microbial product produced by Streptomyces sp. with anti-proliferative activity against cancer cells, acts as a specific iron chelator and binds both Fe(II) and Fe(III) ions and forms a 2:1 chelator-iron complex with a redox-inactive center. |
| PC-24826 |
SF2768
Copper chelator, Antifungal
|
SF2768 (RK-276A) is a diisonitrile antibiotic and specific copper chelator, exhibits potent antifungal activity against C. albicans with IC50 of 0.01 uM. |
| PC-24659 |
PanK inhibitor MNS
Fungal PanK inhibitor
|
PanK inhibitor MNS is a broad-spectrum antifungal, fungal-selective inhibitor of PanK with IC50 of 1.13 μM and 17.74 μM against CaCab1p and AfPanKp respectively, directly engages and inhibits PanK to block CoA production. |
| PC-23890 |
MN-I-157
Yck2 inhibitor
|
MN-I-157 is a specific inhibitor of fungal casein kinase 1 (CK1) family member Yck2 with sub-micromolar potencey. |
| PC-23889 |
YK-I-02
Yck2 inhibitor
|
YK-I-02 is a specific inhibitor of fungal casein kinase 1 (CK1) family member Yck2 with sub-micromolar potencey, 8- to 20-fold selectivity over CK1α but less than 3-fold selectivity over p38α. |
| PC-23301 |
APX2020
Gwt1 inhibitor
|
APX2020 is a novel potent small molecule inhibitor of fungal Gwt1, has MIC of 0.016-0.031 ug/ mL against C. neoformans, C. gattii, Candida albicans. |
| PC-23300 |
APX2096
Gwt1 inhibitor
|
APX2096 is the prodrug of APX2039, which is a novel potent small molecule inhibitor of fungal Gwt1, reduces fungal burden in vivo. |
| PC-23299 |
APX2039
Gwt1 inhibitor
|
APX2039 is a novel potent small molecule inhibitor of fungal Gwt1, has MIC of 0.008-0.031 ug/ mL against C. neoformans, C. gattii, Candida albicans. |
| PC-23185 |
Iodiconazole
Antifungal
|
Iodiconazole is a potent azole drug with strong antifungal activity (Candida albicans, MIC<0.0625 ug/mL). |
