| Cat. No. |
Product Name |
Information |
| PC-43006 |
trans-C75
FASN inhibitor
|
trans-C75 is an enantiomer of FASN inhibitor C75, which is a synthetic, slow-binding inhibitor of mammalian FAS, binds to and inhibits mammalian FAS and inhibits fatty acid synthesis in human cancer cells (SKBR3 cells ID50=3.2 ug/mL). |
| PC-43005 |
FASN inhibitor C75
FASN inhibitor
|
FASN inhibitor C75 is a synthetic, slow-binding inhibitor of mammalian fatty acid synthesis (FASN, FAS), binds to and inhibits mammalian FAS and inhibits fatty acid synthesis in human cancer cells (SKBR3 cells ID50=5.0 ug/mL). |
| PC-42976 |
GSK2194069
FASN inhibitor
|
GSK2194069 is a potent and specific inhibitor of the β-ketoacyl reductase (KR) activity of human fatty acid synthase (hFAS) with IC50 of 7.7 nM (CoA release). |
| PC-62734 |
TVB-3166
FASN inhibitor
|
TVB-3166 is an orally-available, reversible, potent, and selective fatty acid synthase (FASN) inhibitor with biochemical IC50 of 42 nM. |
| PC-70282 |
Cerulenin
FASN inhibitor
|
Cerulenin is an antifungal antibiotic that inhibits fatty acid synthase (FASN), also blocks cellular proliferation of KRAS-associated lung cancer cells. |
| PC-27174 |
IQZ-1
FASN expression inhibitor
|
IQZ-1 isa small molecule inhibitor of FASN expression, inhibits FASN transcription at least via the proximal sterol regulatory elements of the FASN promoter, significantly reduces HCV intracellular viral RNA levels and markedly suppresses infectious particle production. |