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首页-小分子抑制剂&激动剂-Autophagy

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Cat. No. Product Name Information
PC-60601

Lys05

Autophagy inhibitor, Kir4.1 inhibitor

Lys05 (Lys01 trihydrochloride, PS-1001) is the water-soluble salt of Lys01, is a 10-fold more potent lysosomal autophagy inhibitor than hydroxychloroquine (HCQ), also is a Kir4.1 inhibitor.
PC-60600

Lys01

Autophagy inhibitor

Lys01 is a 10-fold more potent lysosomal autophagy inhibitor than hydroxychloroquine (HCQ).
PC-60599

ROC-325

Autophagy inhibitor

ROC-325 (ROC 325, ROC325) is a novel, orally available inhibitor of lysosomal-mediated autophagy.
PC-60217

AUTEN-67

MTMR14 inhibitor, autophagy inducer

AUTEN-67 is a small molecule autophagy enhancer that specificly inhibits myotubularin-related phosphatase MTMR14.
PC-70067

AUTEN-99

MTMR14 inhibitor, autophagy inducer

AUTEN-99 is a small molecule autophagy enhancer that inhibit the myotubularin-related phosphatase MTMR14/Jumpy.
PC-70066

AUTEN-99 hydrobromide

MTMR14 inhibitor, autophagy inducer

A small molecule autophagy enhancer that inhibit the myotubularin-related phosphatase MTMR14/Jumpy.
PC-45633

Hemin

CLEC-2 agonist, HO-1 inducer

Hemin is an iron-containing porphyrin as heme oxygenase (HO)-1 inducer, also is a CLEC-2 agonist that induces CLEC-2-mediated platelet aggregation.
PC-42080

SMER28

VCP/p97 activator

SMER28 is a small-molecule enhancer/inducer of Autophagy, SMER28 is a small molecule activator of VCP/p97.
PC-42248

STF-62247

Autophagy inducer

STF-62247 is a small molecule Autophagy inducer that induces autophagy and selectively induces lethality in VHL-deficient RCC cells.
PC-45515

SMER-18

Autophagy inducer

SMER-18 is a small molecule autophagy enhancer that induces autophagy independently of rapamycin in mammalian cells and enhances the clearance of autophagy substrates such as mutant huntingtin and A53T alpha-synuclein.
PC-25750

GW296115

BRSK2 inhibitor

GW296115 is a potent inhibitor of brain-specific serine/threonine protein kinases BRSK2 with IC50 of 8.4 nM and 21 nM for BRSK2 and BRSK1 respectively.
PC-25554

Autophagy inhibitor 5j

Autophagy inhibitor

Autophagy inhibitor 5j is a potent late-stage autophagy inhibitor, trigger an ER stress response and interfere with cathepsin D maturation, potentially contributing to altered lysosomal trafficking.

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