| Cat. No. |
Product Name |
Information |
| PC-22544 |
UW-MD-95
BChE inhibitor
|
UW‐MD‐95 is a potent pseudo‐irreversible butyrylcholinesterase (BChE) inhibitor with IC50 of 60 nM, does not inhibit AChE, shows potent neuroprotective in the Aβ25‐35 model of AD. |
| PC-22297 |
S21-1011
BChE inhibitor
|
S21-1011 is a potent, selective, BBB-penetrant butyrylcholinesterase (BChE) inhibitor with IC50 of 59 nM and 162 nM for eqBChE and hBChE, respectively. |
| PC-60067 |
AD-35 hydrochloride
|
A donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates. |
| PC-60065 |
AD-35 phosphate
|
A donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates. |