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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-11β-HSD

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Cat. No. Product Name Information
PC-24097

Emodin

11β-HSD1 inhibitor, Nrf2 activator

Emodin (Frangula emodin) is an anthraquinone derivative with anti-SARS-CoV activity, blocks the SARS coronavirus spike protein and ACE2 interaction, also inhibits casein kinase-2 (CK2), also activates Nrf2 and effectively targets PD pathology.
PC-20841

AMG221

11beta-HSD1 inhibitor

AMG221 is a potent, selective orally active 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) inhibitor with Ki of 12.8 nM and cell IC50 of 10.1 nM.

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