pan-Trk PAM 1 | pan-Trk PAM | Probechem Biochemicals

Chemical Structure : pan-Trk PAM 1

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pan-Trk PAM 1 (IGF-1R modulator 1)

货号: PC-28111Not For Human Use, Lab Use Only.

pan-Trk PAM 1 (IGF-1R modulator 1) is a potent, pan-TRK positive allosteric modulator (PAM) with EC50s of 0.29 μM (FGFR1), 0.25 μM (IGF1R), 0.34 μM (TrkA), 0.39 μM (TrkB), modulates neurotrophin signalling.

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生物&药学活性

pan-Trk PAM 1 (IGF-1R modulator 1) is a potent, pan-TRK positive allosteric modulator (PAM) with EC50s of 0.29 μM (FGFR1), 0.25 μM (IGF1R), 0.34 μM (TrkA), 0.39 μM (TrkB), modulates neurotrophin signalling.

物理化学性质&存储条件

分子量	387.40
分子式	C22H17N3O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1-(3-methyl-4-phenoxyphenyl)-3-phenyl-

参考文献

1. Patent WO2019162702 A1 ((Example 5).

pan-Trk PAM 1 (IGF-1R modulator 1)

生物&药学活性

物理化学性质&存储条件

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pan-Trk PAM 1 (IGF-1R modulator 1)

生物&药学活性

物理化学性质&存储条件

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