kb NB142-70 (kb NB142-70) | PKD inhibitor | Probechem Biochemicals

Chemical Structure : kb NB 142-70

CAS No.: 1233533-04-4

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kb NB 142-70 (kb NB142-70, kb-NB142-70)

货号: PC-63036Not For Human Use, Lab Use Only.

kb NB142-70 is a potent and selective PKD inhibitor with IC50 of 28.3 nM, 58.7 nM and 53.2 nM for PKD1, PKD2, and PKD3, respectively.

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5 mg	￥780	In stock
10 mg	￥1180	In stock
25 mg	￥1980	In stock
50 mg	￥3480	In stock
100 mg		Get quote

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生物&药学活性

kb NB142-70 is a potent and selective PKD inhibitor with IC50 of 28.3 nM, 58.7 nM and 53.2 nM for PKD1, PKD2, and PKD3, respectively.
kb NB142 70 displays 10-fold increase in the in vitro PKD1 inhibitory potency versus CID755673.
kb NB142 70 inhibits PC-3, PANC-1, CFPAC-1 cellular growth with IC50 of 5-30 uM.

物理化学性质&存储条件

分子量	251.318
分子式	C11H9NO2S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3,4-dihydro-9-hydroxy-[1]benzothieno[2,3-f]-1,4-thiazepin-5(2H)-one

参考文献

1. Bravo-Altamirano K, et al. ACS Med Chem Lett. 2011 Feb 14;2(2):154-159.

2. Guo J, et al. Cancer Chemother Pharmacol. 2013 Feb;71(2):331-44.

kb NB 142-70 (kb NB142-70, kb-NB142-70)

生物&药学活性

物理化学性质&存储条件

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kb NB 142-70 (kb NB142-70, kb-NB142-70)

生物&药学活性

物理化学性质&存储条件

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