iZMYND8-34

Chemical Structure : iZMYND8-34

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货号: PC-24337Not For Human Use, Lab Use Only.

iZMYND8-34 is a small molecule inhibitor of histone reader zinc finger MYND-type containing 8 (ZMYND8), inhibits ZMYND8 histone recognition, effectively blocks neuroendocrine prostate cancer (NEPC) development.

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iZMYND8-34 is a small molecule inhibitor of histone reader zinc finger MYND-type containing 8 (ZMYND8) with IC50 of 0.66 uM, inhibits ZMYND8 histone recognition, effectively blocks neuroendocrine prostate cancer (NEPC) development.

物理化学性质&存储条件

分子量	449.42
分子式	C22H19N5O6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	9-(benzo[d][1,3]dioxol-5-yl)-2-(3-ethoxy-2-hydroxyphenyl)-7-methyl-8-oxo-8,9-dihydro-7H-purine-6-carboxamide

参考文献

1. Wang H, et al. Nat Cancer. 2025 Mar 18. doi: 10.1038/s43018-025-00928-z.

iZMYND8-34

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iZMYND8-34

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