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hClpP inhibitor TG42

Chemical Structure : hClpP inhibitor TG42

CAS No.: 2611398-90-2

hClpP inhibitor TG42

货号: PC-25349Not For Human Use, Lab Use Only.

hClpP inhibitor TG42 is a potent and selective inhibitor of hClpP with IC50 of 0.39 uM, efficiently blocks proteolysis.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

hClpP inhibitor TG42 is a potent and selective inhibitor of hClpP with IC50 of 0.39 uM, efficiently blocks proteolysis.
TG42 reduces cell viability in Huh7 cells, induces apoptotic cell death in Huh7 cells.

物理化学性质&存储条件

分子量 394.39
分子式 C24H14N2O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(1,3,4-oxadiazol-2-yl)phenyl 2-(2-ethynylnaphtho[2,1-b]furan-1-yl)acetate

参考文献

1. Thomas F Gronauer, et al. Chem Commun (Camb). 2018 Aug 28;54(70):9833-9836.

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